A heterodimer formed by bone morphogenetic protein 9 (BMP9) and BMP10 provides most BMP biological activity in plasma

Bone morphogenetic protein 9 (BMP9) and BMP10 are the two high-affinity ligands for the endothelial receptor activin receptor-like kinase 1 (ALK1) and are key regulators of vascular remodeling. They are both present in the blood, but their respective biological activities are still a matter of debat...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Tillet, Emmanuelle, Ouarné, Marie, Desroches-Castan, Agnès, Mallet, Christine, Subileau, Mariela, Didier, Robin, Lioutsko, Anna, Belthier, Guillaume, Feige, Jean-Jacques, Bailly, Sabine
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052235/
https://ncbi.nlm.nih.gov/pubmed/29789425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002968
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