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Frontotemporal Dementia-Associated N279K Tau Mutation Localizes at the Nuclear Compartment
Tau is a microtubule-associated protein that plays an important role in Alzheimer’s disease and related tauopathies. Approximately one-half of all cases of Frontotemporal dementia with parkinsonism-17 (FTDP-17) are caused by mutations in the MAPT gene. The N279K mutation is one of the three mutation...
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| Veröffentlicht in: | Front Cell Neurosci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052045/ https://ncbi.nlm.nih.gov/pubmed/30050413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00202 |
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