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Inactivation of TCA cycle enhances Staphylococcus aureus persister cell formation in stationary phase

Persister cells constitute a small subpopulation of bacteria that display remarkably high antibiotic tolerance and for pathogens such as Staphylococcus aureus are suspected as culprits of chronic and recurrent infections. Persisters formed during exponential growth are characterized by low ATP level...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Wang, Ying, Bojer, Martin Saxtorph, George, Shilpa Elizabeth, Wang, Zhihao, Jensen, Peter Ruhdal, Wolz, Christiane, Ingmer, Hanne
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052003/
https://ncbi.nlm.nih.gov/pubmed/30022089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29123-0
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