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Tyr(1)-ψ[(Z)CF=CH]-Gly(2) Fluorinated Peptidomimetic Improves Distribution and Metabolism Properties of Leu-Enkephalin
Opioid peptides are key regulators in cellular and intercellular physiological responses, and could be therapeutically useful for modulating several pathological conditions. Unfortunately, the use of peptide-based agonists to target centrally located opioid receptors is limited by poor physicochemic...
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| Publié dans: | ACS Chem Neurosci |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6051889/ https://ncbi.nlm.nih.gov/pubmed/29648788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00085 |
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