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Tyr(1)-ψ[(Z)CF=CH]-Gly(2) Fluorinated Peptidomimetic Improves Distribution and Metabolism Properties of Leu-Enkephalin

Opioid peptides are key regulators in cellular and intercellular physiological responses, and could be therapeutically useful for modulating several pathological conditions. Unfortunately, the use of peptide-based agonists to target centrally located opioid receptors is limited by poor physicochemic...

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Dettagli Bibliografici
Pubblicato in:ACS Chem Neurosci
Autori principali: Altman, Ryan A., Sharma, Krishna K., Rajewski, Lian G., Toren, Paul C., Baltezor, Michael J., Pal, Mohan, Karad, Somnath N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051889/
https://ncbi.nlm.nih.gov/pubmed/29648788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00085
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