HPV Oncogene Manipulation Using Nonvirally Delivered CRISPR/Cas9 or Natronobacterium gregoryi Argonaute

CRISPR/Cas9 technology enables targeted gene editing; yet, the efficiency and specificity remain unsatisfactory, particularly for the nonvirally delivered, plasmid‐based CRISPR/Cas9 system. To tackle this, a self‐assembled micelle is developed and evaluated for human papillomavirus (HPV) E7 oncogene...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Lao, Yeh‐Hsing, Li, Mingqiang, Gao, Madeleine A., Shao, Dan, Chi, Chun‐Wei, Huang, Dantong, Chakraborty, Syandan, Ho, Tzu‐Chieh, Jiang, Weiqian, Wang, Hong‐Xia, Wang, Sihong, Leong, Kam W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051382/
https://ncbi.nlm.nih.gov/pubmed/30027026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201700540
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