Mutational Analysis of Oncogenic AKT1 Gene Associated with Breast Cancer Risk in the High Altitude Ecuadorian Mestizo Population

Breast cancer is the leading cause of cancer-related death among women worldwide. AKT1 encodes the kinase B alpha protein. The rs121434592, rs12881616, rs11555432, rs11555431, rs2494732, and rs3803304 single nucleotide polymorphisms have been identified in the AKT1 kinase gene. Activated AKT1 phosph...

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Publicat a:Biomed Res Int
Autors principals: López-Cortés, Andrés, Leone, Paola E., Freire-Paspuel, Byron, Arcos-Villacís, Nathaly, Guevara-Ramírez, Patricia, Rosales, Felipe, Paz-y-Miño, César
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051326/
https://ncbi.nlm.nih.gov/pubmed/30065942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7463832
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