LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial–mesenchymal transition through the Notch1 signaling pathway

Leucine‐rich repeat‐containing G protein‐coupled receptor 5 (LGR5) plays a vital role in the development of malignant tumors; however, its biological role and underlying mechanism in epithelial ovarian cancer (EOC) remain unclear. In this study, we aimed to investigate the biological function and cl...

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Publicado en:Cancer Med
Autores principales: Liu, Wenxue, Zhang, Jing, Gan, Xupei, Shen, Fangqian, Yang, Xiaoming, Du, Na, Xia, Dandan, Liu, Lei, Qiao, Lianqiao, Pan, Jufang, Sun, Yunyan, Xi, Xiaowei
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cancer Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051213/
https://ncbi.nlm.nih.gov/pubmed/29777575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1485
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