Thrombopoietin knock-in augments platelet generation from human embryonic stem cells

BACKGROUND: Refinement of therapeutic-scale platelet production in vitro will provide a new source for transfusion in patients undergoing chemotherapy or radiotherapy. However, procedures for cost-effective and scalable platelet generation remain to be established. METHODS: In this study, we establi...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Zhang, Leisheng, Liu, Cuicui, Wang, Hongtao, Wu, Dan, Su, Pei, Wang, Mengge, Guo, Jiaojiao, Zhao, Shixuan, Dong, Shuxu, Zhou, Wen, Arakaki, Cameron, Zhang, Xiaobing, Zhou, Jiaxi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050740/
https://ncbi.nlm.nih.gov/pubmed/30016991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0926-x
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