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A quantitative systems pharmacology (QSP) model for Pneumocystis treatment in mice
BACKGROUND: The yeast-like fungi Pneumocystis, resides in lung alveoli and can cause a lethal infection known as Pneumocystis pneumonia (PCP) in hosts with impaired immune systems. Current therapies for PCP, such as trimethoprim-sulfamethoxazole (TMP-SMX), suffer from significant treatment failures...
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| Pubblicato in: | BMC Syst Biol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6050661/ https://ncbi.nlm.nih.gov/pubmed/30016951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0603-9 |
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