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Globular-shaped variable lymphocyte receptors B antibody multimerized by a hydrophobic clustering in hagfish

In hagfish and lampreys, two representative jawless vertebrates, the humoral immunity is directly mediated by variable lymphocyte receptors B (VLRBs). Both monomeric VLRBs are structurally and functionally similar, but their C-terminal tails differ: lamprey VLRB has a Cys-rich tail that forms disulf...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Jaesung, Im, Se Pyeong, Lee, Jung Seok, Lazarte, Jassy Mary S., Kim, Si Won, Jung, Jae Wook, Kim, Jong Yong, Kim, Young Rim, Lee, Sangmin, Kim, Gwang Joong, Jung, Hyun Suk, Lee, Kyun Oh, Adams, Alexandra, Thompson, Kim D., Jung, Tae Sung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050320/
https://ncbi.nlm.nih.gov/pubmed/30018426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29197-w
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