Various roles of heme oxygenase-1 in response of bone marrow macrophages to RANKL and in the early stage of osteoclastogenesis

Heme oxygenase-1 (HO-1; encoded by Hmox1), a downstream target of the Nrf2 transcription factor, has been postulated to be a negative regulator of osteoclasts (OCLs) differentiation. Here, we further explored such a hypothesis by examining HO-1 effects in different stages of osteoclastogenesis. We c...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Florczyk-Soluch, Urszula, Józefczuk, Ewelina, Stępniewski, Jacek, Bukowska-Strakova, Karolina, Mendel, Mateusz, Viscardi, Monika, Nowak, Witold Norbert, Józkowicz, Alicja, Dulak, Józef
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050304/
https://ncbi.nlm.nih.gov/pubmed/30018287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29122-1
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