Generation of sphingosine-1-phosphate is enhanced in biliary tract cancer patients and is associated with lymphatic metastasis

Lymphatic metastasis is known to contribute to worse prognosis of biliary tract cancer (BTC). Recently, sphingosine-1-phosphate (S1P), a bioactive lipid mediator generated by sphingosine kinase 1 (SPHK1), has been shown to play an important role in lymphangiogenesis and lymph node metastasis in seve...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Hirose, Yuki, Nagahashi, Masayuki, Katsuta, Eriko, Yuza, Kizuki, Miura, Kohei, Sakata, Jun, Kobayashi, Takashi, Ichikawa, Hiroshi, Shimada, Yoshifumi, Kameyama, Hitoshi, McDonald, Kerry-Ann, Takabe, Kazuaki, Wakai, Toshifumi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050292/
https://ncbi.nlm.nih.gov/pubmed/30018456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29144-9
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki