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Characterization of Disulfide Linkages in Proteins by 193 nm Ultraviolet Photodissociation (UVPD) Mass Spectrometry

Deciphering disulfide bond patterns in proteins remains a significant challenge. In the present study, inter-linked disulfide bonds connecting peptide chains are homolytically cleaved with 193 nm ultraviolet photodissociation (UVPD). Analysis of insulin showcased the ability of UVPD to cleave multip...

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Bibliografiset tiedot
Julkaisussa:Anal Chem
Päätekijät: Quick, M. Montana, Crittenden, Christopher M., Rosenberg, Jake A., Brodbelt, Jennifer S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050148/
https://ncbi.nlm.nih.gov/pubmed/29902373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b01556
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