Exceptional response to pembrolizumab in a metastatic, chemotherapy/radiation-resistant ovarian cancer patient harboring a PD-L1-genetic rearrangement

PURPOSE: Ovarian carcinoma no longer responsive to surgery and chemotherapy remains an incurable disease. Alternative therapeutic options remain desperately needed. EXPERIMENTAL DESIGN: We describe a heavily pretreated ovarian cancer patient with recurrent disease experiencing a remarkable clinical...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Bellone, Stefania, Buza, Natalia, Choi, Jungmin, Zammataro, Luca, Gay, Laurie, Elvin, Julia, Rimm, David L., Liu, Yuting, Ratner, Elena S., Schwartz, Peter E., Santin, Alessandro D.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050068/
https://ncbi.nlm.nih.gov/pubmed/29351920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1805
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