Exceptional response to pembrolizumab in a metastatic, chemotherapy/radiation-resistant ovarian cancer patient harboring a PD-L1-genetic rearrangement

PURPOSE: Ovarian carcinoma no longer responsive to surgery and chemotherapy remains an incurable disease. Alternative therapeutic options remain desperately needed. EXPERIMENTAL DESIGN: We describe a heavily pretreated ovarian cancer patient with recurrent disease experiencing a remarkable clinical...

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Publicat a:Clin Cancer Res
Autors principals: Bellone, Stefania, Buza, Natalia, Choi, Jungmin, Zammataro, Luca, Gay, Laurie, Elvin, Julia, Rimm, David L., Liu, Yuting, Ratner, Elena S., Schwartz, Peter E., Santin, Alessandro D.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050068/
https://ncbi.nlm.nih.gov/pubmed/29351920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1805
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