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Dual roles for ATP in the regulation of phase separated protein aggregates in Xenopus oocyte nucleoli

For many proteins, aggregation is one part of a structural equilibrium that can occur. Balancing productive aggregation versus pathogenic aggregation that leads to toxicity is critical and known to involve adenosine triphosphate (ATP) dependent action of chaperones and disaggregases. Recently a seco...

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Udgivet i:eLife
Main Authors: Hayes, Michael H, Peuchen, Elizabeth H, Dovichi, Norman J, Weeks, Daniel L
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050040/
https://ncbi.nlm.nih.gov/pubmed/30015615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35224
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