No association between IFNL3 (IL28B) genotype and response to peginterferon alfa-2a in HBeAg-positive or -negative chronic hepatitis B

BACKGROUND & AIMS: It has yet to be firmly established whether host IFNL3 (IL28B) genotype influences interferon responsiveness in patients with chronic hepatitis B. We investigated associations between single-nucleotide polymorphisms (SNPs) in the IFNL3 region and response to peginterferon alfa...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Wei, Lai, Wedemeyer, Heiner, Liaw, Yun-Fan, Chan, Henry Lik-Yuen, Piratvisuth, Teerha, Marcellin, Patrick, Jia, Jidong, Tan, Deming, Chow, Wan-Cheng, Brunetto, Maurizia R., Diago, Moisés, Gurel, Selim, Morozov, Viacheslav, He, Hua, Zhu, Yonghong, Wat, Cynthia, Surujbally, Bernadette, Thompson, Alexander J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049926/
https://ncbi.nlm.nih.gov/pubmed/30016335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199198
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