Polymorphisms in DNA mismatch repair pathway genes predict toxicity and response to cisplatin chemoradiation in head and neck squamous cell carcinoma patients

Head and neck squamous cell carcinoma (HNSCC) is treated with cisplatin (CDDP) and radiotherapy (RT), and distinct results are observed among patients with similar clinicopathological aspects. This prospective study aimed to investigate whether MLH1 c.-93G>A (rs1800734), MSH2 c.211+9C>G (rs230...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Nogueira, Guilherme Augusto Silva, Costa, Ericka Francislaine Dias, Lopes-Aguiar, Leisa, Lima, Tathiane Regine Penna, Visacri, Marília Berlofa, Pincinato, Eder Carvalho, Lourenço, Gustavo Jacob, Calonga, Luciane, Mariano, Fernanda Viviane, Altemani, Albina Messias de Almeida Milani, Altemani, João Maurício Carrasco, Moriel, Patrícia, Chone, Carlos Takahiro, Ramos, Celso Dario, Lima, Carmen Silvia Passos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049861/
https://ncbi.nlm.nih.gov/pubmed/30038702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25268
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