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Site-selective C–C modification of proteins at neutral pH using organocatalyst-mediated cross aldol ligations
The bioconjugation of proteins with small molecules has proved an invaluable strategy for probing and perturbing biological mechanisms. The general use of chemical methods for protein functionalisation can be limited however by the requirement for complicated reaction partners to be present in large...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6049525/ https://ncbi.nlm.nih.gov/pubmed/30061990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01617h |
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