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The Role of Adenosine Tone and Adenosine Receptors in Huntington's Disease

Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a mutation in the IT15 gene that encodes for the huntingtin protein. Mutated hungtingtin, although widely expressed in the brain, predominantly affects striato-pallidal neurons, particularly enriched with adenosine A...

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Detalhes bibliográficos
Publicado no:J Caffeine Adenosine Res
Main Authors: Blum, David, Chern, Yijuang, Domenici, Maria Rosaria, Buée, Luc, Lin, Chien-Yu, Rea, William, Ferré, Sergi, Popoli, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049521/
https://ncbi.nlm.nih.gov/pubmed/30023989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/caff.2018.0006
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