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Guide-substrate base-pairing requirement for box H/ACA RNA-guided RNA pseudouridylation

Box H/ACA RNAs are a group of small RNAs found in abundance in eukaryotes (as well as in archaea). Although their sequences differ, eukaryotic box H/ACA RNAs all share the same unique hairpin-hinge-hairpin-tail structure. Almost all of them function as guides that primarily direct pseudouridylation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:RNA
Hauptverfasser: De Zoysa, Meemanage D., Wu, Guowei, Katz, Raviv, Yu, Yi-Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049503/
https://ncbi.nlm.nih.gov/pubmed/29871894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.066837.118
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