A Respiratory Syncytial Virus Vaccine Based on the Small Hydrophobic Protein Ectodomain Presented With a Novel Lipid-Based Formulation Is Highly Immunogenic and Safe in Adults: A First-in-Humans Study

BACKGROUND: Respiratory syncytial virus infection can cause lower respiratory tract infection in older adults comparable to influenza, but no vaccines are available. METHODS: This was a randomized, observer-blinded, first-in-humans study of a novel synthetic RSV antigen based on the ectodomain of th...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Langley, Joanne M, MacDonald, Lisa D, Weir, Genevieve M, MacKinnon-Cameron, Donna, Ye, Lingyun, McNeil, Shelly, Schepens, Bert, Saelens, Xavier, Stanford, Marianne M, Halperin, Scott A
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049039/
https://ncbi.nlm.nih.gov/pubmed/29617814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy177
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