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Membrane flow drives an adhesion-independent amoeboid cell migration mode

Cells migrate by applying rearward forces against extracellular media. It is unclear how this is achieved in amoeboid migration, which lacks adhesions typical of lamellipodia-driven mesenchymal migration. To address this question, we developed optogenetically controlled models of lamellipodia-driven...

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Foilsithe in:Dev Cell
Main Authors: O’Neill, Patrick R., Castillo-Badillo, Jean A., Meshik, Xenia, Kalyanaraman, Vani, Melgarejo, Krystal, Gautam, N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048972/
https://ncbi.nlm.nih.gov/pubmed/29937389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.05.029
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