PEGylated self-assembled enzyme-responsive nanoparticles for effective targeted therapy against lung tumors

BACKGROUND: Matrix-metalloproteinases, which are overexpressed in many types of cancer, can be applied to improve the bioavailability of chemotherapeutic drugs and guide therapeutic targeting. Thus, we aimed to develop enzyme-responsive nanoparticles based on a functionalized copolymer (mPEG-Peptide...

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Gepubliceerd in:J Nanobiotechnology
Hoofdauteurs: Guo, Fangyuan, Wu, Jiangqing, Wu, Wenchao, Huang, Dongxue, Yan, Qinying, Yang, Qingliang, Gao, Ying, Yang, Gensheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048871/
https://ncbi.nlm.nih.gov/pubmed/30012166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0384-8
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