Assessment of the efficacy of repeated instillations of mitomycin C mixed with a thermosensitive hydrogel in an orthotopic rat bladder cancer model

BACKGROUND: We investigated a thermoreversible hydrogel that is highly viscous at body temperature, while fluid-like at a low temperature, thus aiming for a slow and prolonged intravesical drug release. Our study purposed to assess antitumor efficacy of mitomycin C (MMC) mixed with hydrogel in an or...

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Detalhes bibliográficos
Publicado no:Ther Adv Urol
Main Authors: van Valenberg, F. Johannes P., Strauss-Ayali, Dalit, Agmon-Gerstein, Yael, Friedman, Astar, Arentsen, Harm C., Schaafsma, H. Ewout, Witjes, J. Alfred, Oosterwijk, Egbert
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048623/
https://ncbi.nlm.nih.gov/pubmed/30034540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756287218762064
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