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Tenofovir alafenamide in the treatment of chronic hepatitis B virus infection: rationale and clinical trial evidence

Tenofovir alafenamide (TAF), a novel prodrug of tenofovir was developed to deliver enhanced antiviral potency and reduced systemic toxicities by more efficient intracellular delivery of the active metabolite tenofovir disphosphate than tenofovir disoproxil fumarate (TDF). In two randomized, double-b...

詳細記述

保存先:
書誌詳細
出版年:Therap Adv Gastroenterol
主要な著者: Byrne, Ruth, Carey, Ivana, Agarwal, Kosh
フォーマット: Artigo
言語:Inglês
出版事項: SAGE Publications 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048601/
https://ncbi.nlm.nih.gov/pubmed/30034532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284818786108
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