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Molecular model of human tropoelastin and implications of associated mutations

Protein folding poses unique challenges for large, disordered proteins due to the low resolution of structural data accessible in experiment and on the basis of short time scales and limited sampling attainable in computation. Such molecules are uniquely suited to accelerated-sampling molecular dyna...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Tarakanova, Anna, Yeo, Giselle C., Baldock, Clair, Weiss, Anthony S., Buehler, Markus J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048532/
https://ncbi.nlm.nih.gov/pubmed/29946030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801205115
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