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Molecular model of human tropoelastin and implications of associated mutations

Protein folding poses unique challenges for large, disordered proteins due to the low resolution of structural data accessible in experiment and on the basis of short time scales and limited sampling attainable in computation. Such molecules are uniquely suited to accelerated-sampling molecular dyna...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Tarakanova, Anna, Yeo, Giselle C., Baldock, Clair, Weiss, Anthony S., Buehler, Markus J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048532/
https://ncbi.nlm.nih.gov/pubmed/29946030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801205115
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