Sex-chromosome dosage effects on gene expression in humans

A fundamental question in the biology of sex differences has eluded direct study in humans: How does sex-chromosome dosage (SCD) shape genome function? To address this, we developed a systematic map of SCD effects on gene function by analyzing genome-wide expression data in humans with diverse sex-c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Raznahan, Armin, Parikshak, Neelroop N., Chandran, Vijay, Blumenthal, Jonathan D., Clasen, Liv S., Alexander-Bloch, Aaron F., Zinn, Andrew R., Wangsa, Danny, Wise, Jasen, Murphy, Declan G. M., Bolton, Patrick F., Ried, Thomas, Ross, Judith, Giedd, Jay N., Geschwind, Daniel H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048519/
https://ncbi.nlm.nih.gov/pubmed/29946024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802889115
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