Pressure Overload in Mice With Haploinsufficiency of Striated Preferentially Expressed Gene Leads to Decompensated Heart Failure

Striated preferentially expressed gene (Speg) is a member of the myosin light chain kinase family of proteins. Constitutive Speg deficient (Speg(−/−)) mice develop a dilated cardiomyopathy, and the majority of these mice die in utero or shortly after birth. In the present study we assessed the impor...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Shu, Chang, Huang, He, Xu, Ying, Rota, Marcello, Sorrentino, Andrea, Peng, Yuan, Padera, Robert F., Huntoon, Virginia, Agrawal, Pankaj B., Liu, Xiaoli, Perrella, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048438/
https://ncbi.nlm.nih.gov/pubmed/30042693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00863
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