Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

Glucagon secreted from the pancreatic alpha-cells is essential for regulation of blood glucose levels. However, glucagon may play an equally important role in the regulation of amino acid metabolism by promoting ureagenesis. We hypothesized that disruption of glucagon receptor signaling would lead t...

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Publicat a:Am J Physiol Endocrinol Metab
Autors principals: Galsgaard, Katrine D., Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen S., Vilstrup, Hendrik, Prehn, Cornelia, Adamski, Jerzy, Jepsen, Sara L., Hartmann, Bolette, Hunt, Jenna, Charron, Maureen J., Pedersen, Jens, Wewer Albrechtsen, Nicolai J., Holst, Jens J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048389/
https://ncbi.nlm.nih.gov/pubmed/28978545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00198.2017
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