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Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

Glucagon secreted from the pancreatic alpha-cells is essential for regulation of blood glucose levels. However, glucagon may play an equally important role in the regulation of amino acid metabolism by promoting ureagenesis. We hypothesized that disruption of glucagon receptor signaling would lead t...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Galsgaard, Katrine D., Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen S., Vilstrup, Hendrik, Prehn, Cornelia, Adamski, Jerzy, Jepsen, Sara L., Hartmann, Bolette, Hunt, Jenna, Charron, Maureen J., Pedersen, Jens, Wewer Albrechtsen, Nicolai J., Holst, Jens J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048389/
https://ncbi.nlm.nih.gov/pubmed/28978545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00198.2017
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