Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

Glucagon secreted from the pancreatic alpha-cells is essential for regulation of blood glucose levels. However, glucagon may play an equally important role in the regulation of amino acid metabolism by promoting ureagenesis. We hypothesized that disruption of glucagon receptor signaling would lead t...

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Detalles Bibliográficos
Publicado en:Am J Physiol Endocrinol Metab
Main Authors: Galsgaard, Katrine D., Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen S., Vilstrup, Hendrik, Prehn, Cornelia, Adamski, Jerzy, Jepsen, Sara L., Hartmann, Bolette, Hunt, Jenna, Charron, Maureen J., Pedersen, Jens, Wewer Albrechtsen, Nicolai J., Holst, Jens J.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048389/
https://ncbi.nlm.nih.gov/pubmed/28978545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00198.2017
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