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Acidosis and Phosphate Directly Reduce Myosin’s Force-Generating Capacity Through Distinct Molecular Mechanisms
Elevated levels of the metabolic by-products, including acidosis (i.e., high [H(+)]) and phosphate (P(i)) are putative agents of muscle fatigue; however, the mechanism through which they affect myosin’s function remain unclear. To elucidate these mechanisms, we directly examined the effect of acidos...
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| Publicado no: | Front Physiol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6048269/ https://ncbi.nlm.nih.gov/pubmed/30042692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00862 |
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