Interaction of WBP2 with ERα increases doxorubicin resistance of breast cancer cells by modulating MDR1 transcription

BACKGROUND: Surgery combined with new adjuvant chemotherapy is the primary treatment for early stage invasive and advanced stage breast cancer. Growing evidence indicates that patients with ERα-positive breast cancer show poor response to chemotherapeutics. However, ERα-mediated drug-resistant mecha...

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Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Chen, Shuai, Wang, Han, Li, Zhi, You, Jun, Wu, Qiu-Wan, Zhao, Can, Tzeng, Chi-Meng, Zhang, Zhi-Ming
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048156/
https://ncbi.nlm.nih.gov/pubmed/29937544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0119-5
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