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Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo

Photoacoustic (PA) computed tomography (PACT) benefits from genetically encoded probes with photochromic behavior, which dramatically increase detection sensitivity and specificity through photoswitching and differential imaging. Starting with a DrBphP bacterial phytochrome, we have engineered a nea...

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Vydáno v:Nat Commun
Hlavní autoři: Li, Lei, Shemetov, Anton A., Baloban, Mikhail, Hu, Peng, Zhu, Liren, Shcherbakova, Daria M., Zhang, Ruiying, Shi, Junhui, Yao, Junjie, Wang, Lihong V., Verkhusha, Vladislav V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048155/
https://ncbi.nlm.nih.gov/pubmed/30013153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05231-3
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