Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo

Photoacoustic (PA) computed tomography (PACT) benefits from genetically encoded probes with photochromic behavior, which dramatically increase detection sensitivity and specificity through photoswitching and differential imaging. Starting with a DrBphP bacterial phytochrome, we have engineered a nea...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Li, Lei, Shemetov, Anton A., Baloban, Mikhail, Hu, Peng, Zhu, Liren, Shcherbakova, Daria M., Zhang, Ruiying, Shi, Junhui, Yao, Junjie, Wang, Lihong V., Verkhusha, Vladislav V.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048155/
https://ncbi.nlm.nih.gov/pubmed/30013153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05231-3
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