Impact of super-disintegrants and film thickness on disintegration time of strip films loaded with poorly water-soluble drug microparticles

Although strip films are a promising platform for delivery of poorly water-soluble drug particles via slurry casting, the effect of critical materials attributes (CMAs), e.g., super-disintegrants on critical quality attributes (CQAs), including film disintegration time (DT), remains under-explored....

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Zhang, Lu, Aloia, Marie, Pielecha-Safira, Barbara, Lin, Honghao, Rajai, Prarthana Manoj, Kunnath, Kuriakose, Davé, Rajesh N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047912/
https://ncbi.nlm.nih.gov/pubmed/29665377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2018.04.006
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