CRISPR/Cas9 nickase mediated targeting of urokinase receptor gene inhibits neuroblastoma cell proliferation

Neuroblastoma is a tumor arising from pluripotent sympathoadrenal precursor cells of neural cell origin. Neuroblastoma is one of the most aggressive childhood tumors with highly invasive and metastatic potential. The increased expression of urokinase and its receptor is often associated with a negat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rysenkova, Karina D., Semina, Ekaterina V., Karagyaur, Maxim N., Shmakova, Anna A., Dyikanov, Daniyar T., Vasiluev, Petr A., Rubtsov, Yury P., Rubina, Kseniya A., Tkachuk, Vsevolod A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047682/
https://ncbi.nlm.nih.gov/pubmed/30034627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25647
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