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Cancer stem cell molecular reprogramming of the Warburg effect in glioblastomas: a new target gleaned from an old concept

Prior targeted treatment for glioblastoma multiforme (GBM) with anti-angiogenic agents, such as bevacizumab, has been met with limited success potentially owing to GBM tumor's ability to develop a hypoxia-induced escape mechanism – a glycolytic switch from oxidative phosphorylation to glycolysi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:CNS Oncol
Hauptverfasser: Yuen, Carlen A, Asuthkar, Swapna, Guda, Maheedhara R, Tsung, Andrew J, Velpula, Kiran K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Future Medicine Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047435/
https://ncbi.nlm.nih.gov/pubmed/26997129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns-2015-0006
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