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Overexpression of eis without a mutation in promoter region of amikacin- and kanamycin-resistant Mycobacterium tuberculosis clinical strain

BACKGROUND: Aminoglycosides such as amikacin and kanamycin are effective injectable second-line drugs for treatment of multidrug-resistant tuberculosis. Molecular mechanisms underlying aminoglycoside resistance are not well understood. We have previously identified the amikacin- and kanamycin-resist...

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Publicat a:Ann Clin Microbiol Antimicrob
Autors principals: Sowajassatakul, Angkanang, Prammananan, Therdsak, Chaiprasert, Angkana, Phunpruch, Saranya
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047124/
https://ncbi.nlm.nih.gov/pubmed/30008266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12941-018-0285-6
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