Trypanosoma cruzi Infection Induces Cellular Stress Response and Senescence-Like Phenotype in Murine Fibroblasts

Trypanosoma cruzi infects and replicates within a wide variety of immune and non-immune cells. Here, we investigated early cellular responses induced in NIH-3T3 fibroblasts upon infection with trypomastigote forms of T. cruzi. We show that fibroblasts were susceptible to T. cruzi infection and start...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Guimarães-Pinto, Kamila, Nascimento, Danielle Oliveira, Corrêa-Ferreira, Antonia, Morrot, Alexandre, Freire-de-Lima, Celio G., Lopes, Marcela F., DosReis, George A., Filardy, Alessandra A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047053/
https://ncbi.nlm.nih.gov/pubmed/30038622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01569
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