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HPV DNA methylation at the early promoter and E1/E2 integrity: A comparison between HPV16, HPV18 and HPV45 in cervical cancer

OBJECTIVES: To compare and describe type-specific characteristics of HPV16, HPV18 and HPV45 in cervical cancer with respect to 3′LCR methylation and disruption of E1/E2. METHODS: The methylation level of 137 cervical cancer samples (70 with HPV16, 37 with HPV18, and 30 with HPV45) of Brazilian patie...

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Publicat a:Papillomavirus Res
Autors principals: Amaro-Filho, Sérgio Menezes, Pereira Chaves, Cláudia Bessa, Felix, Shayany Pinto, Basto, Diogo Lisbôa, de Almeida, Liz Maria, Moreira, Miguel Angelo Martins
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046686/
https://ncbi.nlm.nih.gov/pubmed/29649654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pvr.2018.04.002
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