Investigating the effect of visfatin on ERalpha phosphorylation (Ser118 and Ser167) and ERE-dependent transcriptional activity

Obesity is associated with higher postmenopausal breast cancer incidence. Visfatin level alteration is one of the mechanisms by which obesity promotes cancer. Ligand-independent activation of estrogen receptor alpha (ERα) is also associated with carcinogenesis. The activity of ERα is modulated throu...

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Veröffentlicht in:EXCLI J
Hauptverfasser: Zangooei, Mohammad, Nourbakhsh, Mitra, Ghahremani, Mohammad Hossein, Meshkani, Reza, Khedri, Azam, Shadboorestan, Amir, Shokri Afra, Hajar, Shahmohamadnejad, Shiva, Mirmiranpour, Hossein, Khaghani, Shahnaz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Leibniz Research Centre for Working Environment and Human Factors 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046625/
https://ncbi.nlm.nih.gov/pubmed/30034315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2018-1299
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