Performing and interpreting individual pharmacokinetic profiles in patients with Hemophilia A or B: Rationale and general considerations

OBJECTIVES: In a separate document, we have provided specific guidance on performing individual pharmacokinetic (PK) studies using limited samples in persons with hemophilia with the goal to optimize prophylaxis with clotting factor concentrates. This paper, intended for clinicians, aims to describe...

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Veröffentlicht in:Res Pract Thromb Haemost
Hauptverfasser: Iorio, Alfonso, Edginton, Andrea N., Blanchette, Victor, Blatny, Jan, Boban, Ana, Cnossen, Marjon, Collins, Peter, Croteau, Stacy E., Fischer, Katheljin, Hart, Daniel P., Ito, Shinya, Korth‐Bradley, Joan, Lethagen, Stefan, Lillicrap, David, Makris, Mike, Mathôt, Ron, Morfini, Massimo, Neufeld, Ellis J., Spears, Jeffrey
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online‐only Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046594/
https://ncbi.nlm.nih.gov/pubmed/30046759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12106
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