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Pharmacokinetics, safety and tolerability of OBE022, a selective prostaglandin F2α receptor antagonist tocolytic: A first‐in‐human trial in healthy postmenopausal women

AIMS: Preterm birth remains a significant risk for later disability. The selective inhibition of the prostaglandin F(2α) receptor has significant advantages for a tocolytic. The prodrug OBE022 and its metabolite OBE002 are novel prostaglandin F(2α) receptor antagonists under development for treating...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Br J Clin Pharmacol
Päätekijät: Pohl, Oliver, Marchand, Line, Gotteland, Jean‐Pierre, Coates, Simon, Täubel, Jörg, Lorch, Ulrike
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046484/
https://ncbi.nlm.nih.gov/pubmed/29708281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13622
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