Repeated social defeat-induced neuroinflammation, anxiety-like behavior and resistance to fear extinction were attenuated by the cannabinoid receptor agonist WIN55,212-2

Psychosocial stress contributes to the development of psychiatric disorders. Repeated social defeat (RSD) is a murine stressor that causes a release of inflammatory monocytes into circulation. Moreover, RSD-induced anxiety-like behavior is dependent on the recruitment of these monocytes to the brain...

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Publicado no:Neuropsychopharmacology
Main Authors: Lisboa, Sabrina Francesca, Niraula, Anzela, Resstel, Leonardo Barbosa, Guimaraes, Francisco Silveira, Godbout, Jonathan P., Sheridan, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046035/
https://ncbi.nlm.nih.gov/pubmed/29786066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0064-2
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