Safety and Optimal Neuroprotection of neu2000 in acute Ischemic stroke with reCanalization: study protocol for a randomized, double-blinded, placebo-controlled, phase-II trial

BACKGROUND: The potential of neuroprotective agents should be revisited in the era of endovascular thrombectomy (EVT) for acute large-artery occlusion because their preclinical effects have been optimized for ischemia and reperfusion injury. Neu2000, a derivative of sulfasalazine, is a multi-target...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Hong, Ji Man, Choi, Mun Hee, Sohn, Sung-Il, Hwang, Yang-Ha, Ahn, Seong Hwan, Lee, Yeong-Bae, Shin, Dong-Ick, Chamorro, Ángel, Choi, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045859/
https://ncbi.nlm.nih.gov/pubmed/30005644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-018-2746-9
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