Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer

BACKGROUND: 5-Hydroxymethylcytosine (5hmC) is converted from 5-methylcytosine (5mC) by a group of enzymes termed ten-eleven translocation (TET) family dioxygenases. The loss of 5hmC has been identified as a hallmark of most types of cancer and is related to tumorigenesis and progression. However, th...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Peng, Ding, Ge, Guangzhe, Gong, Yanqing, Zhan, Yonghao, He, Shiming, Guan, Bao, Li, Yifan, Xu, Ziying, Hao, Han, He, Zhisong, Xiong, Gengyan, Zhang, Cuijian, Shi, Yue, Zhou, Yuanyuan, Ci, Weimin, Li, Xuesong, Zhou, Liqun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045833/
https://ncbi.nlm.nih.gov/pubmed/30005692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0527-7
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