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Calcium-activated chloride channels clamp odor-evoked spike activity in olfactory receptor neurons

The calcium-activated chloride channel anoctamin-2 (Ano2) is thought to amplify transduction currents in olfactory receptor neurons (ORNs), a hypothesis supported by previous studies in dissociated neurons from Ano2(−/−) mice. Paradoxically, despite a reduction in transduction currents in Ano2(−/−)...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zak, Joseph D., Grimaud, Julien, Li, Rong-Chang, Lin, Chih-Chun, Murthy, Venkatesh N.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045664/
https://ncbi.nlm.nih.gov/pubmed/30006552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28855-3
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