Down-regulation of vascular GLP-1 receptor expression in human subjects with obesity

It has been thought that incretin signaling prevents arteriosclerosis, and very recently anti-arteriosclerotic effects through GLP-1 receptor were finally demonstrated in clinical human study. The purpose of this study was to investigate how vascular GLP-1 receptor expression is influenced in human...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kimura, Tomohiko, Obata, Atsushi, Shimoda, Masashi, Shimizu, Ikki, da Silva Xavier, Gabriela, Okauchi, Seizo, Hirukawa, Hidenori, Kohara, Kenji, Mune, Tomoatsu, Moriuchi, Saeko, Hiraoka, Arudo, Tamura, Kentaro, Chikazawa, Genta, Ishida, Atsuhisa, Yoshitaka, Hidenori, Rutter, Guy A., Kaku, Kohei, Kaneto, Hideaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045606/
https://ncbi.nlm.nih.gov/pubmed/30006590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28849-1
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