Transcriptional and post-transcriptional regulation of PenA β-lactamase in acquired Burkholderia pseudomallei β-lactam resistance

Therapy of Burkholderia pseudomallei acute infections is largely limited to a few β-lactam antibiotics such as ceftazidime or meropenem. Although relatively rare, resistance emergence during therapy leads to treatment failures with high mortality rates. In the absence of acquired external resistance...

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Publicado en:Sci Rep
Autores principales: Chirakul, Sunisa, Norris, Michael H., Pagdepanichkit, Sirawit, Somprasong, Nawarat, Randall, Linnell B., Shirley, James F., Borlee, Bradley R., Lomovskaya, Olga, Tuanyok, Apichai, Schweizer, Herbert P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045580/
https://ncbi.nlm.nih.gov/pubmed/30006637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28843-7
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