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UCS protein function is partially restored in the Saccharomyces cerevisiae she4 mutant with expression of the human UNC45-GC, but not UNC45-SM

A dedicated UNC45, Cro1, She4 (UCS) domain-containing protein assists in the Hsp90-mediated folding of the myosin head. Only weak sequence conservation exists between the single UCS protein of simple eukaryotes (She4 in budding yeast) and the two UCS proteins of higher organisms (the general cell an...

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Publicat a:Cell Stress Chaperones
Autors principals: Escalante, Susana Gómez, Brightmore, Joseph A., Piper, Peter W., Millson, Stefan H.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045556/
https://ncbi.nlm.nih.gov/pubmed/29288355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0870-1
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