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Downregulation of exosomal miR-204-5p and miR-632 as a biomarker for FTD: a GENFI study

OBJECTIVE: To determine whether exosomal microRNAs (miRNAs) in cerebrospinal fluid (CSF) of patients with frontotemporal dementia (FTD) can serve as diagnostic biomarkers, we assessed miRNA expression in the Genetic Frontotemporal Dementia Initiative (GENFI) cohort and in sporadic FTD. METHODS: GENF...

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Опубликовано в: :J Neurol Neurosurg Psychiatry
Главные авторы: Schneider, Raphael, McKeever, Paul, Kim, TaeHyung, Graff, Caroline, van Swieten, John Cornelis, Karydas, Anna, Boxer, Adam, Rosen, Howie, Miller, Bruce L, Laforce Jr, Robert, Galimberti, Daniela, Masellis, Mario, Borroni, Barbara, Zhang, Zhaolei, Zinman, Lorne, Rohrer, Jonathan Daniel, Tartaglia, Maria Carmela, Robertson, Janice
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045452/
https://ncbi.nlm.nih.gov/pubmed/29434051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2017-317492
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